SCHEMBL30216888

SCHEMBL30216888

C[Si](C)(C)c1cc(Br)c(-c2c3nc(c(-c4c(Br)cc([Si](C)(C)C)cc4Br)c4ccc([nH]4)c(-c4c(Br)cc([Si](C)(C)C)cc4Br)c4nc(c(-c5c(Br)cc([Si](C)(C)C)cc5Br)c5ccc2[nH]5)C=C4)C=C3)c(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.43
▸ TOP1 P11387 2/20 0.39
▸ CYCS P99999 3/20 0.38
▸ ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011909 0.84 STAT3 (0.51) TERT
SCHEMBL30216873 0.76 TERT (0.39) TERTTOP1CYCSENPP2
SCHEMBL30216896 0.76 STAT3 (0.45) TERTTOP1CYCS
SCHEMBL4256404 0.73 TOP1 (0.41) TERTTOP1CYCSENPP2
SCHEMBL5013034 0.73 TERT (0.39) TERTTOP1CYCS
SCHEMBL4263019 0.73 TERT (0.39) TERTTOP1CYCS
SCHEMBL30644758 0.70 TERT (0.41) TERTTOP1CYCSENPP2
SCHEMBL5013893 0.70 TOP1 (0.51) TERTTOP1CYCSENPP2
SCHEMBL5013908 0.70 TERT (0.39) TERTTOP1CYCSENPP2
SCHEMBL2868186 0.70 TERT (0.39) TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366629-A1 Porphyrin Complexes as Antidotes for Carbon Monoxide Exposure and Methods of Use for Same UNIV CALIFORNIA (US) 2024-11-07 — — US disclosed
WO-2023034447-A1 PORPHYRIN COMPLEXES AS ANTIDOTES FOR CARBON MONOXIDE EXPOSURE AND METHODS OF USE FOR SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366629-A1 Porphyrin Complexes as Antidotes for Carbon Monoxide Exposure and Methods of Use for Same MB, HMBS, HMOX2 TERT 4013/4885TOP1 1356/4885CYCS 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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