Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30216952

COc1ccccc1C[n+]1cccc(CC(=O)NN)c1.COc1ccccc1C[n+]1cccc(CC(=O)NN)c1.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 2/20 0.39
PLA2G2A P14555 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 1/20 0.37
MAPT P10636 3/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.36
CTSD P07339 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL26086337 0.90 ALDH1A1 (0.41) MEN1KMT2ANPC1RAB9ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL26087624 0.89 MEN1 (0.41) MEN1KMT2ANPC1RAB9ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL30216947 0.85 SMN1; SMN2 (0.44) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL30219807 0.83 MEN1 (0.45) MEN1KMT2ANPC1RAB9ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL30216955 0.82 L3MBTL1 (0.40) MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1
SCHEMBL26087619 0.80 MEN1 (0.39) MEN1KMT2ANPC1RAB9ASMN1; SMN2
Trifluoroacetic Acid SCHEMBL30216950 0.77 ACHE (0.34) MEN1KMT2AALDH1A1CYP3A4MAPT
Trifluoroacetic Acid SCHEMBL23326584 0.75 CYP1A2 (0.39) ALDH1A1POLBTDP1CYP3A4KDM4E
Trifluoroacetic Acid SCHEMBL30320103 0.75 L3MBTL1 (0.37) ALDH1A1TDP1CYP3A4CTSDKDM4E
SCHEMBL26087979 0.75 NPSR1 (0.56) MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153565-A1 BENZYLPYRIDINIUM REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2023-03-29 EP disclosed
CN-115667220-A Benzyl pyridinium reagent for mass spectrum 豪夫迈·罗氏有限公司 2023-01-31 CN disclosed