Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980799 | 1.00 | FAAH (0.36) | FAAHGRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23980836 | 0.79 | AOC3 (0.40) | PPARGPPARA | |
| SCHEMBL23980839 | 0.79 | AOC3 (0.40) | PPARGPPARA | |
| SCHEMBL17176032 | 0.76 | SLC6A4 (0.41) | FAAHSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL23980843 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL23980788 | 0.75 | KCNH2 (0.44) | GRM2KCNH2PPARGPPARAGRIN2B | |
| SCHEMBL30217384 | 0.75 | KCNH2 (0.44) | GRM2KCNH2PPARGPPARAGRIN2B | |
| SCHEMBL27287042 | 0.73 | AOC3 (0.36) | PPARGPPARA | |
| SCHEMBL15260689 | 0.72 | PYGL (0.42) | FAAHSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL30467138 | 0.72 | PYGL (0.42) | FAAHSLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143183-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115667250-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-01-31 | — | — | CN | disclosed |