Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 5/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923781 | 0.83 | APLNR (0.45) | APLNRGRIN2BGRIN1 | |
| SCHEMBL31392878 | 0.83 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL22585597 | 0.83 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL31489711 | 0.83 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30218199 | 0.83 | APLNR (0.50) | APLNRGRIN2BGRIN1 | |
| SCHEMBL3940188 | 0.82 | APLNR (0.41) | APLNR | |
| SCHEMBL30839822 | 0.79 | CA1 (0.45) | GRIN2BGRIN1KMT2A | |
| SCHEMBL18224526 | 0.78 | APLNR (0.46) | APLNRGRIN2BGRIN1 | |
| SCHEMBL30318466 | 0.77 | APLNR (0.40) | APLNRGRIN2BGRIN1 | |
| SCHEMBL14646394 | 0.77 | APLNR (0.50) | APLNRGRIN2BGRIN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |