SCHEMBL30218231

SCHEMBL30218231

COc1[nH]nc(C(N)=O)c1CCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MMP2 P08253 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
AURKA O14965 1/20 0.37
RPS6KB1 P23443 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9027126 0.70
SCHEMBL9026702 0.69 NPC1 (0.44) RAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL9026168 0.69 KDM4E (0.58) MEN1KMT2ARAB9AALDH1A1SMN1; SMN2
SCHEMBL9026556 0.68 SLC5A1 (0.40)
Urea SCHEMBL2006220 0.66 FFAR1 (0.62) ALDH1A1SMN1; SMN2LMNATDP1
Carbamic Acid SCHEMBL2222080 0.66 FFAR1 (0.62) ALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL4560742 0.65 SMN1; SMN2 (0.43) SMN1; SMN2LMNA
Carbamic Acid SCHEMBL8092472 0.64 FFAR1 (0.60) ALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL4560244 0.64 PDE4A (0.46) KMT2ARAB9ANPC1CYP3A4CYP2D6
SCHEMBL15964734 0.64 HCAR3 (0.47) KMT2ALMNAAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4125385-A1 COMPOSITIONS AND METHODS FOR CONTROLLING FUNGAL DISEASES IN PLANTS FMC CORPORATION (US) 2023-02-08 EP disclosed