Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027126 | 0.89 | — | — | |
| SCHEMBL9026168 | 0.84 | KDM4E (0.58) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9026556 | 0.80 | SLC5A1 (0.40) | — | |
| SCHEMBL9025697 | 0.77 | KDM4E (0.43) | — | |
| SCHEMBL8536313 | 0.73 | HCAR2 (0.43) | — | |
| SCHEMBL9037584 | 0.73 | HCAR2 (0.36) | — | |
| SCHEMBL9025654 | 0.73 | HCAR2 (0.40) | SMN1; SMN2 | |
| SCHEMBL30529034 | 0.71 | — | — | |
| SCHEMBL5568394 | 0.71 | KDM4E (0.56) | SMN1; SMN2 | |
| Acetone SCHEMBL3486840 | 0.70 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725783-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011905-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-05-04 | — | — | WO | disclosed |