Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423157 | 0.79 | GABRP (0.53) | GAAMAPK1AURKACDK5KDM4E | |
| SCHEMBL4161172 | 0.79 | GABRP (0.53) | GAAMAPK1AURKACDK5KDM4E | |
| SCHEMBL13933686 | 0.78 | DAO (0.57) | SMN1; SMN2GAAMAPK1AURKAPRKCQ | |
| SCHEMBL11436500 | 0.78 | DAO (0.57) | SMN1; SMN2GAAMAPK1EP300KAT2B | |
| SCHEMBL28379997 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAMAPK1EP300KAT2B | |
| SCHEMBL6975916 | 0.76 | NPEPPS (0.54) | SMN1; SMN2GAAMAPK1ALDH1A1KDM4E | |
| SCHEMBL8331276 | 0.74 | KDM4E (0.48) | SMN1; SMN2GAAALOX5NOX4NOX1 | |
| SCHEMBL12661008 | 0.74 | EP300 (0.53) | SMN1; SMN2GAAMAPK1EP300KAT2B | |
| SCHEMBL26646440 | 0.73 | ADORA2B (0.51) | SMN1; SMN2GAAMAPK1ALDH1A1 | |
| SCHEMBL30681658 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAMAPK1EP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759088-B1 | TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS | AlzeCure Pharma AB (SE) | 2023-01-25 | — | — | EP | claimed |