Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTPRG | P23470 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22261444 | 1.00 | CYP1A2 (0.41) | CYP1A2PTPRGRAB9AALDH1A1NPC1 | |
| SCHEMBL22261498 | 0.83 | TSHR (0.42) | CYP1A2RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL22261513 | 0.82 | NR4A1 (0.43) | CYP1A2ALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL20924693 | 0.81 | FFAR1 (0.44) | CYP1A2RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL29773946 | 0.77 | HTR7 (0.35) | RAB9AALDH1A1NPC1SMN1; SMN2LMNA | |
| SCHEMBL28468918 | 0.77 | HTR7 (0.35) | RAB9AALDH1A1NPC1SMN1; SMN2LMNA | |
| SCHEMBL28396513 | 0.76 | RXRA (0.46) | CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL28888266 | 0.75 | MRGPRX4 (0.36) | CYP1A2PTPRGRAB9AALDH1A1NPC1 | |
| SCHEMBL29604543 | 0.75 | MRGPRX4 (0.36) | CYP1A2PTPRGRAB9AALDH1A1NPC1 | |
| SCHEMBL28391132 | 0.75 | RORC (0.33) | CYP1A2PTPRGRAB9ANPC1PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667269-B | Pyridone condensed ring derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-115667269-A | Pyridone-containing fused ring derivative inhibitor, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |