Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858842 | 0.85 | TAS1R3 (0.55) | ARTAS1R3TAS1R1PARP1 | |
| SCHEMBL701970 | 0.82 | TAS1R3 (0.50) | ARTAS1R3TAS1R1MAPTTDP1 | |
| SCHEMBL9548004 | 0.82 | TAS1R3 (0.50) | TAS1R3TAS1R1MAPTTDP1 | |
| SCHEMBL8606616 | 0.81 | TAS1R3 (0.49) | ARTAS1R3TAS1R1MAPTTDP1 | |
| SCHEMBL15855901 | 0.78 | AR (0.48) | ARPARP1TDP1 | |
| SCHEMBL21374189 | 0.78 | ALDH1A1 (0.57) | TAS1R3TAS1R1MAPTTDP1 | |
| SCHEMBL13495890 | 0.78 | PARP1 (0.40) | ARPARP1MAPTTDP1 | |
| SCHEMBL1002832 | 0.77 | PRSS1 (0.61) | PARP1MAPTTDP1 | |
| SCHEMBL29503140 | 0.77 | PRSS1 (0.61) | PARP1MAPTTDP1 | |
| SCHEMBL858817 | 0.77 | AR (0.57) | ARPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-116715625-A | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | disclosed |