Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046535 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24046638 | 0.78 | ALDH1A1 (0.49) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30219770 | 0.78 | ALDH1A1 (0.49) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30219722 | 0.72 | ALDH1A1 (0.43) | CYP3A4ALDH1A1MAPTAGTR1SMN1; SMN2 | |
| SCHEMBL24046641 | 0.72 | ALDH1A1 (0.43) | CYP3A4ALDH1A1MAPTAGTR1SMN1; SMN2 | |
| SCHEMBL24495130 | 0.70 | ALDH1A1 (0.56) | CYP3A4CYP2D6ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15928754 | 0.68 | MAPT (0.44) | CYP3A4CYP2D6ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25695773 | 0.65 | CYP3A4 (0.39) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2522557 | 0.65 | ALDH1A1 (0.52) | ALDH1A1MAPTAGTR1SMN1; SMN2GAA | |
| SCHEMBL11343092 | 0.65 | ABL1 (0.55) | ALDH1A1MAPTAGTR1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153175-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |