Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046641 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL30219774 | 0.85 | TSHR (0.41) | ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL24046642 | 0.85 | TSHR (0.41) | ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL30219731 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL30219732 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL30219764 | 0.72 | CYP3A4 (0.41) | MAPTCYP3A4SMN1; SMN2TP53CCR2 | |
| SCHEMBL24046542 | 0.72 | CYP3A4 (0.41) | MAPTCYP3A4SMN1; SMN2TP53CCR2 | |
| SCHEMBL24046535 | 0.72 | CYP3A4 (0.44) | ALDH1A1MAPTCYP3A4SMN1; SMN2AGTR1 | |
| SCHEMBL30219763 | 0.72 | CYP3A4 (0.44) | ALDH1A1MAPTCYP3A4SMN1; SMN2AGTR1 | |
| SCHEMBL25695740 | 0.70 | CYP3A4 (0.41) | MAPTCYP3A4SMN1; SMN2TP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153175-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |