Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30220566 | 0.87 | KMT2A (0.44) | JMJD6CLK1CLK3DYRK1ALMNA | |
| SCHEMBL30220595 | 0.85 | JMJD6 (0.40) | JMJD6CLK1CLK3DYRK1ALMNA | |
| SCHEMBL2579457 | 0.77 | ALDH1A1 (0.57) | LMNAGAAKDM4EALDH1A1HPGD | |
| SCHEMBL20505664 | 0.73 | CLK1 (0.39) | CLK1CLK3DYRK1ALMNAGAA | |
| SCHEMBL30220535 | 0.72 | JMJD6 (0.41) | JMJD6LMNAMAPTKMT2AKDM4E | |
| SCHEMBL8687098 | 0.72 | ALDH1A1 (0.51) | LMNAGAAMAPTKMT2AKDM4E | |
| SCHEMBL24896372 | 0.72 | GPR35 (0.40) | LMNARXFP1KDM4EALDH1A1HPGD | |
| SCHEMBL29367154 | 0.71 | KMT2A (0.43) | LMNAMAPTKMT2ARXFP1KDM4E | |
| SCHEMBL25205865 | 0.71 | KMT2A (0.43) | LMNAMAPTKMT2ARXFP1KDM4E | |
| SCHEMBL23931478 | 0.70 | ALDH1A1 (0.56) | GAAMAPTKMT2ARXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370207-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |