Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11357288 | 1.00 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL7176348 | 1.00 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL10454811 | 1.00 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL11587441 | 1.00 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL6445984 | 1.00 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL27832806 | 0.93 | NAAA (0.48) | NAAACES2GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL1538407 | 0.89 | ALDH1A1 (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11357290 | 0.88 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| SCHEMBL30203815 | 0.88 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD | |
| SCHEMBL302224 | 0.88 | NAAA (0.54) | NAAACES2GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112980281-B | Water-blocking and air-blocking protective material and preparation method thereof | 深圳市志凌伟业光电有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-112980281-A | Water-blocking gas-barrier protective material and preparation method thereof | 深圳市志凌伟业光电有限公司 | 2021-06-18 | — | — | CN | claimed |
| EP-2930208-B1 | METHOD OF COMPATIBILIZATION OF POLYPROPYLENE BLENDS, POLYPROPYLENE BLEND AND USE THEREOF, PRODUCT AND COMPATIBILIZING INITIATING AGENT OF A BLEND POLYPROPYLENE | BRASKEM SA (BR) | 2017-11-01 | — | — | EP | claimed |
| EP-2930208-A1 | POLYPROPYLENE BLEND COMPATIBILIZATION METHOD, POLYPROPYLENE BLEND AND USE THEREOF, POLYPROPYLENE BLEND PRODUCT AND COMPATIBILIZATION INITIATOR | Braskem S.A. (BR) | 2015-10-14 | — | — | EP | claimed |
| CN-122078017-A | Packaging film with easily-torn barrier layer and preparation method thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119798727-A | Crosslinked polyethylene insulating material with intrinsic self-repairing and recyclable characteristics, and preparation method and application thereof | 北京科技大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118737555-B | Fire-resistant wire and cable for building and preparation method thereof | 云南巨力电缆股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118769650-A | Easily-torn packaging film and preparation method thereof | 安姆科科技研发有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118737555-A | Fire-resistant wire and cable for building and preparation method thereof | 云南巨力电缆股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| EP-4219131-A1 | HIGH PERFORMANCE POLYOLEFIN FOR MATERIAL EXTRUSION | Braskem America, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3732020-B1 | METHOD OF ADDITIVE MANUFACTURING USING HIGH PERFORMANCE POLYOLEFINS | BRASKEM AMERICA INC (US) | 2023-05-17 | — | — | EP | disclosed |
| CN-114761444-A | Hydrogel precursor liquid, method for producing hydrogel production product, and hydrogel production product | 株式会社理光 | 2022-07-15 | — | — | CN | disclosed |
| EP-1538186-A1 | Solid binding agents hardened by means of radiation containing reactive diluents | Bayer MaterialScience AG (DE) | 2005-06-08 | — | — | EP | disclosed |
| EP-1522560-A1 | A radiation curable binder containing carboxylic acid ester | Bayer MaterialScience AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| EP-1516012-A1 | GLASS FIBRE REINFORCED PLASTICS | Bayer MaterialScience AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| US-20040195731-A1 | Glass fiber reinforced plastics | BAYER AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040132909-A1 | Dual cure systems | ALLNEX NETHERLANDS B.V. (NL) | 2004-07-08 | — | — | US | disclosed |
| US-20040006152-A1 | Radiation-curing coating compositions | COVESTRO DEUTSCHLAND AG (DE) | 2004-01-08 | — | — | US | disclosed |
| WO-2003106542-A1 | GLASS FIBRE REINFORCED PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-24 | — | — | WO | disclosed |
| EP-0106991-B1 | PROCESS FOR PREPARING COPOLYMERS OF MONOETHYLENICALLY UNSATURATED MONO- AND DICARBOXYLIC ACIDS (ANHYDRIDE) | BASF Aktiengesellschaft (DE) | 1987-05-13 | — | — | EP | disclosed |