Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664445 | 0.82 | CA1 (0.60) | CISD1KMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3660148 | 0.81 | SRC (0.50) | SRCMAOAMAOBNPC1RAB9A | |
| SCHEMBL32665231 | 0.81 | SRC (0.50) | SRCMAOAMAOBNPC1RAB9A | |
| SCHEMBL18176624 | 0.80 | CISD1 (0.53) | SRCCISD1KMT2AGAAMAPT | |
| Sulfuric Acid SCHEMBL8608191 | 0.80 | NPC1 (0.56) | SRCMAOBNPC1RAB9AKMT2A | |
| SCHEMBL30036812 | 0.79 | MAOA (0.49) | SRCMAOAMAOBNPC1RAB9A | |
| SCHEMBL9157033 | 0.77 | ALDH1A1 (0.62) | MAOAMAOBKMT2AGAAMAPT | |
| SCHEMBL3042573 | 0.76 | STS (0.64) | CISD1KMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL14823100 | 0.76 | SRC (0.56) | SRCMAOAMAOBNPC1RAB9A | |
| SCHEMBL30555891 | 0.76 | MAPT (0.46) | CISD1KMT2AMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141171-A1 | PYRIDINE DERIVATIVE SUBSTITUTED WITH HETEROCYCLE AND PHOSPHONOAMINO AND ANTIFUNGAL AGENT CONTAINING THE SAME | Eisai R&D Management Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |
| EP-0298361-A1 | Liquid detergene containing disulfonated optical brighteners | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |