Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 7/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25313095 | 1.00 | PTH1R (0.34) | PTH1REGLN1ARRAB9ACYP11B1 | |
| SCHEMBL25314565 | 0.83 | PGR (0.36) | PTH1REGLN1 | |
| SCHEMBL30132794 | 0.83 | PGR (0.36) | PTH1REGLN1 | |
| SCHEMBL30227657 | 0.78 | AR (0.36) | EGLN1ARELANE | |
| SCHEMBL25312905 | 0.78 | AR (0.36) | EGLN1ARELANE | |
| SCHEMBL23972244 | 0.78 | ALDH1A1 (0.38) | EGLN1CYP11B1CYP11B2 | |
| SCHEMBL30718077 | 0.78 | ALDH1A1 (0.38) | EGLN1CYP11B1CYP11B2 | |
| SCHEMBL25312867 | 0.78 | MEN1 (0.34) | PTH1RRAB9A | |
| SCHEMBL24687985 | 0.78 | ALDH1A1 (0.38) | EGLN1CYP11B1CYP11B2 | |
| SCHEMBL30227489 | 0.78 | MEN1 (0.34) | PTH1RRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143182-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | Rhizen Pharmaceuticals AG (CH) | 2023-03-08 | — | — | EP | disclosed |