Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30227941 | 0.88 | KCNA3 (0.44) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30227976 | 0.79 | KCNA3 (0.48) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30228317 | 0.78 | KCNA3 (0.47) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30228319 | 0.78 | KCNA3 (0.47) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30228381 | 0.78 | KCNA3 (0.56) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30228231 | 0.77 | KCNA3 (0.53) | KCNA3CA9CA12MAOBMAOA | |
| Hydrochloric Acid SCHEMBL30228355 | 0.77 | KCNA3 (0.55) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL30228324 | 0.77 | ALDH1A1 (0.49) | KCNA3CA9CA12ALDH2ALDH1A1 | |
| SCHEMBL30228296 | 0.77 | KCNA3 (0.46) | KCNA3CA9CA12MAOBALDH2 | |
| SCHEMBL31710481 | 0.76 | KCNA3 (0.52) | KCNA3CA9CA12MAOBALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |