Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228249 | 0.89 | NPC1 (0.42) | NPC1RAB9ACTDSP1TDP1CA9 | |
| SCHEMBL30228041 | 0.85 | KDM4E (0.43) | NPC1RAB9ACTDSP1TDP1CA9 | |
| SCHEMBL30227908 | 0.85 | ALDH1A1 (0.44) | NPC1RAB9ACTDSP1TDP1CA9 | |
| SCHEMBL30227987 | 0.82 | DPP4 (0.45) | NPC1RAB9ACTDSP1TDP1CA9 | |
| SCHEMBL30227961 | 0.82 | KDM4E (0.44) | NPC1RAB9ACTDSP1TDP1ALDH1A1 | |
| SCHEMBL30228136 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9ACTDSP1TDP1CA9 | |
| SCHEMBL30228345 | 0.80 | CA12 (0.39) | NPC1RAB9ATDP1CA9CA12 | |
| SCHEMBL30228076 | 0.80 | CA12 (0.39) | NPC1RAB9ATDP1CA9CA12 | |
| SCHEMBL30228038 | 0.80 | CA12 (0.39) | NPC1RAB9ATDP1CA9CA12 | |
| SCHEMBL30228316 | 0.80 | SLC18A1 (0.47) | NPC1RAB9ACTDSP1TDP1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |