Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.65 |
| ▸ | CA9 | Q16790 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 2/20 | 0.65 |
| ▸ | CASP7 | P55210 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228381 | 0.83 | KCNA3 (0.56) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30228412 | 0.83 | KCNA3 (0.62) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5691199 | 0.83 | KCNA3 (0.62) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22431749 | 0.82 | CA12 (0.70) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30228248 | 0.82 | CA12 (0.70) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30227952 | 0.82 | KCNA3 (0.59) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL30228355 | 0.82 | KCNA3 (0.55) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27886610 | 0.80 | CA9 (0.68) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30228119 | 0.80 | KCNA3 (0.56) | CA12CA9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30231784 | 0.80 | KDM4E (0.67) | CA12CA9ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |