Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228352 | 0.88 | KCNA3 (0.55) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL19309434 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNAL3MBTL1CA12CA9 | |
| SCHEMBL30228517 | 0.81 | KCNA3 (0.54) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL30228286 | 0.81 | KCNA3 (0.47) | KCNA3ALDH1A1CA9MAOAKDM4E | |
| SCHEMBL30228412 | 0.81 | KCNA3 (0.62) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL5691199 | 0.81 | KCNA3 (0.62) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL30228220 | 0.80 | KCNA3 (0.48) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL22431749 | 0.80 | CA12 (0.70) | KCNA3ALDH1A1LMNACA12CA9 | |
| SCHEMBL30227952 | 0.80 | KCNA3 (0.59) | KCNA3ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL30228337 | 0.80 | CA12 (0.65) | KCNA3ALDH1A1LMNAL3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |