Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262604 | 0.79 | MAOB (0.60) | KDM4EALDH1A1CA9CA12SMN1; SMN2 | |
| SCHEMBL20848064 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1ARHPGD | |
| SCHEMBL30762931 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1ARHPGD | |
| SCHEMBL20839145 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1ARHPGD | |
| SCHEMBL30228305 | 0.78 | ALDH1A1 (0.58) | KDM4EALDH1A1GAACA9CA2 | |
| SCHEMBL30231641 | 0.78 | CA12 (0.49) | KDM4EALDH1A1CA9CA2CA12 | |
| SCHEMBL30228363 | 0.77 | ALDH1A1 (0.52) | ALPLALPIKDM4EALDH1A1GAA | |
| SCHEMBL20839359 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1GAACA9CA12 | |
| SCHEMBL20839408 | 0.76 | CA12 (0.69) | KDM4EALDH1A1GAACA9CA12 | |
| SCHEMBL30228226 | 0.76 | CA12 (0.69) | KDM4EALDH1A1GAACA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |