Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.51 |
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781779 | 1.00 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL28859930 | 0.91 | HTR2C (0.49) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL614853 | 0.86 | HTR2C (0.63) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL29691303 | 0.86 | HTR2C (0.63) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL4890789 | 0.84 | HTR2C (0.64) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL2782627 | 0.84 | HTR2C (0.49) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL2782414 | 0.81 | HTR2C (0.57) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL2783536 | 0.77 | HTR6 (0.56) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL2783823 | 0.76 | HTR2C (0.73) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3761304 | 0.76 | DRD2 (0.45) | SLC6A4HTR2CHTR2AHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |