Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228519 | 0.85 | DRD2 (0.47) | P2RY14SSTR1SSTR4 | |
| SCHEMBL20588412 | 0.82 | SSTR1 (0.44) | P2RY14GRK2RENTACR1SSTR1 | |
| SCHEMBL20588417 | 0.82 | SSTR1 (0.44) | P2RY14GRK2RENTACR1SSTR1 | |
| SCHEMBL20588415 | 0.82 | SSTR1 (0.44) | P2RY14GRK2RENTACR1SSTR1 | |
| Hydrochloric Acid SCHEMBL4884562 | 0.82 | MAOA (0.52) | GRK2RENCYP3A4TDP1USP2 | |
| Hydrochloric Acid SCHEMBL4884589 | 0.82 | MAOA (0.52) | GRK2RENCYP3A4TDP1USP2 | |
| Hydrochloric Acid SCHEMBL4884571 | 0.82 | MAOA (0.52) | GRK2RENCYP3A4TDP1USP2 | |
| SCHEMBL30228685 | 0.81 | SSTR4 (0.43) | P2RY14HTR2ASSTR1SSTR4 | |
| Hydrochloric Acid SCHEMBL4914643 | 0.81 | TACR1 (0.44) | P2RY14GRK2RENCYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL4914648 | 0.81 | TACR1 (0.44) | P2RY14GRK2RENCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |