Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228516 | 0.85 | P2RY14 (0.41) | SSTR4SSTR1P2RY14 | |
| SCHEMBL23858278 | 0.84 | SSTR1 (0.47) | HTR2CSSTR4SSTR1 | |
| SCHEMBL30075780 | 0.84 | SSTR1 (0.47) | HTR2CSSTR4SSTR1 | |
| SCHEMBL23858281 | 0.84 | SSTR1 (0.47) | HTR2CSSTR4SSTR1 | |
| SCHEMBL23858279 | 0.84 | SSTR1 (0.47) | HTR2CSSTR4SSTR1 | |
| SCHEMBL30228685 | 0.80 | SSTR4 (0.43) | SSTR4SSTR1P2RY14 | |
| SCHEMBL23873173 | 0.79 | HTR2C (0.60) | DRD2HTR2CP2RY14 | |
| SCHEMBL26515976 | 0.79 | HTR2C (0.60) | DRD2HTR2CP2RY14 | |
| SCHEMBL26115367 | 0.79 | HTR2C (0.60) | DRD2HTR2CP2RY14 | |
| SCHEMBL30228264 | 0.79 | P2RY14 (0.37) | HTR2CSSTR4SSTR1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |