Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455702 | 0.98 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL6839720 | 0.98 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL856486 | 0.93 | — | — | |
| SCHEMBL2999774 | 0.82 | — | — | |
| SCHEMBL5249440 | 0.78 | LMNA (0.68) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL9680510 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL2818271 | 0.78 | KMT2A (0.48) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL4434498 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL2371891 | 0.76 | LMNA (0.65) | ALDH1A1LMNAMEN1BLMHBB | |
| SCHEMBL2371134 | 0.76 | LMNA (0.65) | ALDH1A1LMNAMEN1BLMHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-01 | — | — | US | disclosed |
| US-8212055-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-07-03 | — | — | US | disclosed |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-12 | — | — | US | disclosed |
| US-7678900-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-12 | — | — | US | disclosed |
| US-7470785-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1848778-A2 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | North Carolina State University (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006089122-A2 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-08-24 | — | — | WO | disclosed |
| US-6946552-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050165228-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-28 | — | — | US | disclosed |
| US-6559374-B2 | Multilayer solar cells | NORTH CAROLINA STATE UNIVERSITY | 2003-05-06 | — | — | US | disclosed |
| EP-1303884-A1 | SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020185173-A1 | Solar cells incorporating light harvesting arrays | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-12-12 | — | — | US | disclosed |
| WO-2002092601-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-11-21 | — | — | WO | disclosed |
| US-6420648-B1 | SOLAR CELLS | NORTH CAROLINA STATE UNIVERSITY | 2002-07-16 | — | — | US | disclosed |
| US-6407330-B1 | A CIRCUIT ELECTRICALLY COUPLED TO SAID SOLAR CELL; LIGHT HARVESTING RODS OF NON-DISCOTIC BACKBONE POLYMER CONTAINING CHROMOPHORE GROUPS | NORTH CAROLINA STATE UNIVERSITY | 2002-06-18 | — | — | US | disclosed |
| US-20020033192-A1 | Trans beta substituted chlorins and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-03-21 | — | — | US | disclosed |
| WO-2002009196-A1 | LIGHT HARVESTING ARRAYS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2002008230-A1 | TRANS BETA SUBSTITUTED CHLORINS AND METHODS OF MAKING AND USING THE SAME | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2002009197-A1 | SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | ALDH1A1 3657/4885LMNA 4378/4885MEN1 394/4885 |
| US-20050165228-A1 | Refined routes to chlorin building blocks | DHFR, DDT, SHARPIN | ALDH1A1 3657/4885LMNA 4378/4885MEN1 394/4885 |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | ALDH1A1 3657/4885LMNA 4378/4885MEN1 394/4885 |
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | ALDH1A1 3657/4885LMNA 4378/4885MEN1 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.