Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338713 | 0.83 | NR3C1 (0.44) | ADRB2ADRB1L3MBTL1NR3C1CYP2D6 | |
| SCHEMBL18551296 | 0.79 | KDM4E (0.45) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL14423843 | 0.78 | APP (0.42) | KDM4EMAPTADRB2ADRB1NR3C1 | |
| SCHEMBL2504209 | 0.78 | KDM4E (0.68) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL13930293 | 0.77 | LOXL2 (0.50) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL12926311 | 0.77 | MAOB (0.48) | KDM4EMAPTADRB2ADRB1NR3C1 | |
| Water SCHEMBL6392774 | 0.76 | ESR1 (0.56) | KDM4ECYP3A4MAPTL3MBTL1TAAR1 | |
| Hydrochloric Acid SCHEMBL30925271 | 0.75 | KDM4E (0.74) | LOXL2KDM4ECYP3A4MAPTNCF1 | |
| SCHEMBL660708 | 0.75 | SLC6A4 (0.47) | NOS3NOS1NOS2HTR7SIGMAR1 | |
| SCHEMBL20943201 | 0.75 | NOS3 (0.42) | LOXL2KDM4ECYP3A4MAPTNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395549-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | Oerth Bio LLC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | OERTH BIO LLC (US) | 2023-03-09 | — | — | WO | disclosed |