SCHEMBL3023576

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18569097	0.79	MAPK1 (0.32)	MAPK1HSD17B10
	SCHEMBL1653384	0.78	TUBB4A (0.42)	MAPK1HSD17B10
	SCHEMBL1654258	0.77	MAPK1 (0.38)	BRD4MAPK1HSD17B10ATAD2
	SCHEMBL3027155	0.73	BRD4 (0.41)	BRD4MAPK1HSD17B10ATAD2PIM1
	SCHEMBL18568972	0.72	MAPK1 (0.32)	MAPK1HSD17B10
	SCHEMBL18568656	0.71	MAPK1 (0.31)	MAPK1HSD17B10
	SCHEMBL3029448	0.71	BRD4 (0.53)	BRD4MAPK1HSD17B10ATAD2PIM1
	SCHEMBL1653191	0.71	LMNA (0.36)	MAPK1HSD17B10
	SCHEMBL3421907	0.70	BRD4 (0.42)	BRD4MAPK1HSD17B10ATAD2
	SCHEMBL1653063	0.70	NFKBIA (0.47)	BRD4HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.