Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 7/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354984 | 1.00 | HSPD1 (0.50) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL7773503 | 1.00 | HSPD1 (0.50) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL8990173 | 1.00 | HSPD1 (0.50) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL7063689 | 0.98 | CPT2 (0.52) | HSPD1BLMHSPE1CPT2ACLY | |
| Hydrochloric Acid SCHEMBL28182927 | 0.95 | CPT2 (0.48) | HSPD1BLMHSPE1CPT2ACLY | |
| Phosphoric Acid SCHEMBL28919711 | 0.93 | FDPS (0.47) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL2979037 | 0.92 | CPT2 (0.53) | HSPD1BLMHSPE1CPT2ACLY | |
| Glycerin SCHEMBL28861479 | 0.91 | CPT2 (0.46) | HSPD1BLMHSPE1CPT2ACLY | |
| SCHEMBL11225040 | 0.87 | HSPD1 (0.43) | HSPD1BLMHSPE1CPT2ACLY | |
| O-Xylene SCHEMBL29004500 | 0.85 | GAA (0.42) | HSPD1BLMHSPE1CPT2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262118-A | Application of alidenafil or salt thereof in preparation of medicines for preventing or treating ischemic brain injury | 真奥金银花药业有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115776982-A | 3- ({ 5-chloro-1- [3- (methylsulfonyl) propyl ] -1H-indol-2-yl } methyl) -1- (2,2,2-trifluoroethyl) -1,3-dihydro-2H-imidazo [4,5-c ] pyridin-2-one in the form of the hemi (L) -tartrate salt and pharmaceutical compositions containing same | 爱尔兰詹森科学公司 | 2023-03-10 | — | — | CN | disclosed |