Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 7/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236384 | 0.98 | HSPD1 (0.50) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL8990173 | 0.98 | HSPD1 (0.50) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL1354984 | 0.98 | HSPD1 (0.50) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL7773503 | 0.98 | HSPD1 (0.50) | CPT2ACLYHSPD1BLMHSPE1 | |
| Hydrochloric Acid SCHEMBL28182927 | 0.96 | CPT2 (0.48) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL2979037 | 0.94 | CPT2 (0.53) | CPT2ACLYHSPD1BLMHSPE1 | |
| Glycerin SCHEMBL28861479 | 0.93 | CPT2 (0.46) | CPT2ACLYHSPD1BLMHSPE1 | |
| Phosphoric Acid SCHEMBL28919711 | 0.92 | FDPS (0.47) | CPT2ACLYHSPD1BLMHSPE1 | |
| O-Xylene SCHEMBL29004500 | 0.86 | GAA (0.42) | CPT2ACLYHSPD1BLMHSPE1 | |
| SCHEMBL28219381 | 0.86 | ACLY (0.57) | CPT2ACLYHSPD1BLMHSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311265-B1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | TARGACEPT INC (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6743812-B1 | 2,3-DIACYLTARTARIC ACID SALTS OF E-METANICOTINE; NERVOUS SYSTEM DISORDERS; AGONISTS OF SPECIFIC NICOTINIC RECEPTOR SUBTYPES | TARGACEPT, INC. | 2004-06-01 | — | — | US | disclosed |
| EP-1317267-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | Targacept, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1311265-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | Targacept, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6432954-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | TARGACEPT, INC. | 2002-08-13 | — | — | US | disclosed |
| WO-2002005801-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002005798-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |