Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 4/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.43 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574672 | 1.00 | GRM5 (0.48) | GRM5GRM1PDE10AELANEPDK4 | |
| SCHEMBL31009243 | 0.88 | GRM1 (0.50) | GRM5GRM1PDE10APDK4GPR119 | |
| SCHEMBL29668677 | 0.82 | GPR119 (0.44) | GRM5GRM1ELANEKDM1AGPR119 | |
| SCHEMBL22933049 | 0.82 | GPR119 (0.44) | GRM5GRM1ELANEKDM1AGPR119 | |
| SCHEMBL22391958 | 0.82 | GLP1R (0.47) | GRM5GRM1PDE10AELANEGPR119 | |
| SCHEMBL24498578 | 0.82 | GRM1 (0.46) | GRM5GRM1ELANEKDM1AGPR119 | |
| SCHEMBL29947339 | 0.82 | GLP1R (0.47) | GRM5GRM1PDE10AELANEGPR119 | |
| SCHEMBL24400933 | 0.82 | ELANE (0.44) | GRM5GRM1ELANEPDK4KDM1A | |
| SCHEMBL24320715 | 0.81 | KDM1A (0.45) | GRM5GRM1ELANEKDM1AGPR119 | |
| SCHEMBL22932920 | 0.80 | GPR119 (0.47) | GRM5GRM1ELANEKDM1AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667238-B | Five-membered ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-115667238-A | Five-membered ring derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-01-31 | — | — | CN | disclosed |