Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776129 | 1.00 | ADORA2A (0.42) | ADORA2AADORA1ADORA3ADORA2BSLC6A4 | |
| SCHEMBL23212719 | 1.00 | ADORA2A (0.42) | ADORA2AADORA1ADORA3ADORA2BSLC6A4 | |
| SCHEMBL24926667 | 0.85 | ADORA2A (0.47) | ADORA2AADORA1ADORA3ADORA2BSLC6A4 | |
| SCHEMBL24821844 | 0.71 | SNCA (0.34) | — | |
| SCHEMBL3838752 | 0.71 | ADORA2A (0.53) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL29776083 | 0.69 | PDK2 (0.32) | — | |
| SCHEMBL22498581 | 0.69 | PDK2 (0.32) | — | |
| SCHEMBL29656827 | 0.69 | PDK2 (0.32) | — | |
| SCHEMBL22510344 | 0.69 | PDK2 (0.32) | — | |
| SCHEMBL29659844 | 0.69 | PDK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | ELANCO ANIMAL HEALTH GMBH (DE) | 2026-03-24 | — | — | US | disclosed |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | CBR3, CYCS, CWC15 | ADORA2A 3739/4885ADORA1 3418/4885ADORA3 2110/4885 |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | DDT, PRXL2A, CAT | ADORA2A 1546/4885ADORA1 1953/4885ADORA3 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.