Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961899 | 1.00 | MEN1 (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15319487 | 0.82 | AURKA (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15416821 | 0.78 | KDR (0.47) | KDRAURKANPC1ADRA1DADRA1A | |
| SCHEMBL7661585 | 0.77 | AURKA (0.36) | LMNAKDRAURKAADRA1DADRA1A | |
| SCHEMBL29441332 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL11850524 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL3417255 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL249552 | 0.75 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31175932 | 0.75 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31588841 | 0.73 | KMT2A (0.67) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573503-B | Pyrrole derivatives as PLK1 inhibitors | 圣提内尔肿瘤学有限公司 | 2023-03-17 | — | — | CN | disclosed |