Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239797 | 1.00 | MEN1 (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15319487 | 0.82 | AURKA (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL15416821 | 0.78 | KDR (0.47) | KDRAURKANPC1ADRA1DADRA1A | |
| SCHEMBL7661585 | 0.77 | AURKA (0.36) | LMNAKDRAURKAADRA1DADRA1A | |
| SCHEMBL29441332 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL11850524 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL3417255 | 0.76 | NFE2L2 (0.44) | MEN1KMT2AKDRAURKAMAOB | |
| SCHEMBL249552 | 0.75 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31175932 | 0.75 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31588841 | 0.73 | KMT2A (0.67) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603625-B | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-113603625-A | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2021-11-05 | — | — | CN | claimed |
| EP-3038619-B1 | COMPOUND AND METHOD FOR VACCINATION AND IMMUNISATION | PCI BIOTECH AS (NO) | 2023-10-04 | — | — | EP | disclosed |
| CN-113603625-B | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113603625-B | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113603625-A | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113603625-A | Synthetic method of ketorolac intermediate | 南京卓康医药科技有限公司 | 2021-11-05 | — | — | CN | disclosed |
| US-9901636-B2 | Conjugate of a photosensitiser and chitosan and uses thereof | PCI BIOTECH AS (NO) | 2018-02-27 | — | — | US | disclosed |
| CN-104045626-B | Compounds based on 4-phenyl-6-(2,2,2-trifluoro-1-phenyl ethoxy) pyrimidine and application method thereof | 莱西肯医药有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104961747-A | Tetrahydrobenzo [ d ] [1,2,6] oxadinitrogen compound and preparation method thereof | UNIV DALIAN TECH | 2015-10-07 | — | — | CN | disclosed |
| CN-104945403-A | Tetrahydrobenzo [ e ] [1,2,4] triaza compounds and preparation method thereof | UNIV DALIAN TECH | 2015-09-30 | — | — | CN | disclosed |
| EP-0894011-A2 | DELIVERY OF NUCLEIC ACIDS BY PORPHYRINS | INNOVIR LABORATORIES, INC. (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1998006440-A2 | PHENOTYPIC CONVERSION OF CELLS MEDIATED BY EXTERNAL GUIDE SEQUENCES | INNOVIR LABORATORIES, INC. (US) | 1998-02-19 | — | — | WO | disclosed |
| WO-1997033622-A2 | DELIVERY OF NUCLEIC ACIDS BY PORPHYRINS | INNOVIR LABORATORIES, INC. (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5281616-A | Treatment of human immunodeficiency virus infections | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1994-01-25 | — | — | US | disclosed |
| US-5192788-A | PORPHYRIN ANTIVIRAL COMPOSITIONS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5109016-A | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| WO-1989011277-A2 | PORPHYRIN AND PHTHALOCYANINE ANTIVIRAL COMPOSITIONS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| US-4233452-A | TREATMENT AND PREVENTION OF CALCIUM OXALATE UROLITHIASIS | MERCK & CO., INC. (US) | 1980-11-11 | — | — | US | disclosed |
| US-4207329-A | Derivatives of glycolic and glyoxylic acid as inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1980-06-10 | — | — | US | disclosed |