Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18222500 | 0.86 | HTR6 (0.52) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL3017284 | 0.83 | HTR6 (0.68) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL7017328 | 0.81 | HTR6 (0.63) | HTR6MTNR1AMTNR1BPPARGPPARD | |
| SCHEMBL18222528 | 0.79 | HTR6 (0.49) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL3012635 | 0.78 | HTR6 (0.55) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL7018452 | 0.76 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL29169606 | 0.75 | HTR6 (0.67) | HTR6 | |
| SCHEMBL7024537 | 0.75 | HTR6 (0.77) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL18222505 | 0.74 | HTR6 (0.43) | HTR6MTNR1AMTNR1BNQO2PPARG | |
| SCHEMBL18222527 | 0.74 | HTR6 (0.50) | HTR6MTNR1AMTNR1BNQO2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204276-A1 | INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204276-A1 | INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MTNR1A, MTNR1B, IDO1 | HTR6 16/4885MTNR1A 1/4885MTNR1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.