SCHEMBL30249062

SCHEMBL30249062

O=C(O)C=Cc1ccc2c(c1C=CC(=O)O)Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RAB9A P51151 2/20 0.42
HSP90AA1 P07900 2/20 0.42
MITF O75030 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
NFKB1 P19838 1/20 0.41
CA4 P22748 1/20 0.41
SRD5A2 P31213 2/20 0.41
NPC1 O15118 1/20 0.40
PTGER1 P34995 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL29434002 0.95 CA1 (0.41) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
Alcohol SCHEMBL30689895 0.94 RAB9A (0.39) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
Orthocresol SCHEMBL29473411 0.89 NFKB1 (0.43) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
1-Naphthol SCHEMBL31499454 0.87 CA1 (0.41) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL29436954 0.86 HTT (0.36) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL29676550 0.85 HTT (0.36) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL31132409 0.84 CA1 (0.49) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL31499452 0.83 P2RX3 (0.35) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL31499453 0.83 P2RX3 (0.35) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1
SCHEMBL30865644 0.82 RAB9A (0.32) CYP1A2CYP3A4HSD17B10RAB9AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023054118-A1 PHOTOSENSITIVE COMPOSITION, CURED OBJECT, AND ORGANIC-EL DISPLAY DEVICE 東レ株式会社 2023-04-06 WO disclosed