Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13215212 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3024971 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14266421 | 0.91 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14266408 | 0.88 | NR3C1 (0.39) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5111904 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL5111902 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL14266444 | 0.87 | MEN1 (0.38) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6270547 | 0.87 | CHRM3 (0.35) | LMNASMN1; SMN2S1PR1CHRM3LCK | |
| SCHEMBL14266435 | 0.86 | NR3C1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2S1PR1 | |
| SCHEMBL13215922 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | DUNKEL RALF | 2010-08-26 | — | — | US | disclosed |
| US-7728019-B2 | Biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20080085924-A1 | Biphenylcaboxamides | BAYER CROPSCINCE AG (DE) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085924-A1 | Biphenylcaboxamides | AHR, Q6ZSR9, DDT | ALDH1A1 415/4885MEN1 1392/4885KMT2A 177/4885 |
| US-20100216849-A1 | BIPHENYLCARBOXAMIDES | AHR, DDT, MRPL21 | ALDH1A1 478/4885MEN1 1557/4885KMT2A 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.