Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111902 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266418 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266421 | 0.91 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266377 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266424 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266406 | 0.90 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1CYP3A4TSHR | |
| SCHEMBL14266408 | 0.89 | NR3C1 (0.39) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL14266399 | 0.89 | CYP3A4 (0.44) | KMT2ACYP3A4LMNACHRM3 | |
| SCHEMBL14266444 | 0.88 | MEN1 (0.38) | ALDH1A1KMT2AMEN1CYP3A4HSD17B10 | |
| SCHEMBL9979664 | 0.88 | LMNA (0.45) | ALDH1A1KMT2AMEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348350-B2 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms | BAYER CROPSCIENCE AG (DE) | 2008-03-25 | — | — | US | disclosed |
| US-6992098-B2 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms | BAYER CROPSCIENCE AG (DE) | 2006-01-31 | — | — | US | disclosed |
| US-20050182120-A1 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms | ELBE HANS-LUDWIG (DE) | 2005-08-18 | — | — | US | disclosed |
| US-20040053971-A1 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms | BAYER CROPSCIENCE AG (DE) | 2004-03-18 | — | — | US | disclosed |
| EP-1313709-A1 | PYRAZOLYL BIPHENYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002008195-A1 | PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053971-A1 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesired microorganisms | MRPL21, Q6ZSR9, MRM1 | ALDH1A1 967/4885KMT2A 1141/4885MEN1 1530/4885 |
| US-20050182120-A1 | Pyrazolyl biphenyl carboxamides and the use thereof for controlling undesirable microorganisms | DDT, MRPL21, DCXR | ALDH1A1 948/4885KMT2A 784/4885MEN1 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.