Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289855 | 0.81 | HIF1A (0.53) | HIF1ASMN1; SMN2SLC13A5AKR1B1CYP2C19 | |
| SCHEMBL4490230 | 0.72 | CES1 (0.40) | HIF1ASMN1; SMN2CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL4329261 | 0.72 | CYP1A2 (0.36) | HIF1ASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL3864488 | 0.71 | HIF1A (0.47) | HIF1ASMN1; SMN2SLC13A5AKR1B1CYP2C19 | |
| SCHEMBL406701 | 0.69 | CES1 (0.42) | SMN1; SMN2AKR1B1ALDH1A1NPC1RAB9A | |
| SCHEMBL1131124 | 0.68 | RIPK1 (0.56) | SMN1; SMN2CYP2C19CYP2C9RAB9ALMNA | |
| SCHEMBL7355721 | 0.68 | HIF1A (0.43) | HIF1ASMN1; SMN2AKR1B1CYP2C19ALDH1A1 | |
| SCHEMBL1856206 | 0.67 | SMN1; SMN2 (0.46) | HIF1ASMN1; SMN2AKR1B1CYP2C19ALDH1A1 | |
| SCHEMBL182272 | 0.67 | CALM1 (0.44) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL2937880 | 0.67 | NPSR1 (0.43) | SMN1; SMN2ALDH1A1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |