Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947867 | 1.00 | MAOB (0.42) | MAOBMAOACYP2C9MAPTLMNA | |
| SCHEMBL23882692 | 0.84 | MAOB (0.41) | MAOBMAOAMAPTLMNAGRM5 | |
| SCHEMBL23882824 | 0.84 | MAOB (0.41) | MAOBMAOAGRM5 | |
| SCHEMBL12316781 | 0.75 | MAOB (0.44) | MAOBMAOACYP2C9MAPTLMNA | |
| SCHEMBL30251104 | 0.75 | ESR1 (0.51) | MAOBMAOAMAPTLMNAGRM5 | |
| SCHEMBL12316602 | 0.75 | ESR1 (0.51) | MAOBMAOAMAPTLMNAGRM5 | |
| SCHEMBL11352770 | 0.74 | SIRT2 (0.43) | MAOBMAOAMAPTLMNAGRM5 | |
| SCHEMBL7761381 | 0.74 | TDP2 (0.44) | MAOBMAOAMAPTLMNAGRM5 | |
| SCHEMBL1652005 | 0.72 | CYP2C9 (0.37) | MAOACYP2C9MAPTEEF2KSRC | |
| SCHEMBL25181257 | 0.71 | ALDH1A1 (0.38) | MAOBMAOAMAPTLMNAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126835-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |