Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253186 | 0.81 | MTOR (0.48) | PIK3CAPIK3CGMAP4K1MTORCYP11B2 | |
| SCHEMBL5740638 | 0.78 | PTGS2 (0.48) | PIK3CAPTGS2MTORCYP11B2 | |
| SCHEMBL28362833 | 0.72 | F10 (0.53) | PTGS2 | |
| SCHEMBL30253096 | 0.71 | MAP4K1 (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGMAP4K1 | |
| SCHEMBL29865430 | 0.69 | PTGS2 (0.52) | PIK3CAPTGS2MTOR | |
| SCHEMBL8285973 | 0.69 | PTGS2 (0.48) | PTGS2MTOR | |
| SCHEMBL2996200 | 0.69 | PTGS2 (0.50) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS2 | |
| SCHEMBL31333855 | 0.68 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CGMAP4K1 | |
| SCHEMBL2343226 | 0.67 | F10 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS2 | |
| SCHEMBL29462406 | 0.67 | F10 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115715288-A | TYK-2 inhibitors | 百济神州有限公司 | 2023-02-24 | — | — | CN | disclosed |