Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865430 | 0.80 | PTGS2 (0.52) | PTGS2DRD2F10PIK3CAMTOR | |
| SCHEMBL30227277 | 0.80 | PTGS2 (0.46) | PTGS2CYP11B2F10PIK3CA | |
| SCHEMBL198132 | 0.80 | PTGS2 (0.57) | PTGS2F10 | |
| SCHEMBL22797004 | 0.78 | CYP11B2 (0.54) | DRD2DRD3CYP11B2HDAC1ALDH1A1 | |
| SCHEMBL30253230 | 0.78 | PIK3CD (0.47) | PTGS2CYP11B2PIK3CAMTOR | |
| SCHEMBL15713710 | 0.78 | CYP11B2 (0.48) | DRD2DRD3CYP11B2HDAC1ALDH1A1 | |
| SCHEMBL8285973 | 0.77 | PTGS2 (0.48) | PTGS2DRD3F10MTOR | |
| SCHEMBL6068510 | 0.76 | CYP11B2 (0.47) | DRD2DRD3CYP11B2HDAC1ALDH1A1 | |
| SCHEMBL31700253 | 0.76 | GAA (0.58) | DRD2DRD3CYP11B2HDAC1ALDH1A1 | |
| SCHEMBL306879 | 0.76 | GAA (0.58) | DRD2DRD3CYP11B2HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| CN-115003663-A | Novel heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |
| US-11407721-B2 | CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer | AMGEN INC. (US) | 2022-08-09 | — | — | US | disclosed |
| EP-1697353-A2 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS WITH AFFINITY FOR 5-HT1 RECEPTORS | Pfizer Products Incorporated (US) | 2006-09-06 | — | — | EP | disclosed |
| US-20050227980-A1 | Aralkyl and aralkylidene heterocyclic lactam and imides | PFIZER INC. | 2005-10-13 | — | — | US | disclosed |
| US-20050227981-A1 | Aralkyl and aralkylidene heterocyclic lactam and imides | PFIZER INC | 2005-10-13 | — | — | US | disclosed |
| WO-2005061491-A2 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS WITH AFFINITY FOR 5-HT1 RECEPTORS | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | HRH4, HNMT, NNT | PTGS2 269/4885DRD2 3450/4885DRD3 1931/4885 |
| US-20050227981-A1 | Aralkyl and aralkylidene heterocyclic lactam and imides | ARAF, MRPL21, ACSL3 | PTGS2 2236/4885DRD2 166/4885DRD3 89/4885 |
| US-11407721-B2 | CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer | MDM2, TP53, MDM4 | PTGS2 2146/4885DRD2 4865/4885DRD3 4873/4885 |
| US-20050227980-A1 | Aralkyl and aralkylidene heterocyclic lactam and imides | ARAF, MRPL21, ACSL3 | PTGS2 2236/4885DRD2 166/4885DRD3 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.