Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253658 | 0.85 | ALDH1A1 (0.56) | TSHRNPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL12986725 | 0.77 | NTRK1 (0.55) | TSHRNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL15279120 | 0.76 | PTGS2 (0.48) | NPC1MAPTRAB9AGAAALDH1A1 | |
| SCHEMBL680255 | 0.76 | PPARA (0.54) | MAPTGAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL30253451 | 0.75 | GRK2 (0.43) | TSHRNPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL19463471 | 0.74 | MAPT (0.47) | NPC1MAPTGAABRD9CMA1 | |
| SCHEMBL16557177 | 0.74 | GFER (0.60) | TSHRMAPTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL15279145 | 0.73 | RPA1 (0.46) | SMN1; SMN2MAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL15279133 | 0.71 | ALDH1A1 (0.43) | TSHRSMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL15279139 | 0.70 | ALDH1A1 (0.42) | TSHRSMN1; SMN2GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040686-A1 | PYRIDAZINONE COMPOUND, PREPARATION METHOD, HERBICIDE COMPOSITION AND USE THEREOF | 江苏中旗科技股份有限公司 | 2023-03-23 | — | — | WO | disclosed |