Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377699 | 0.80 | KEAP1 (0.52) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL21777246 | 0.79 | KCNJ6 (0.45) | KMT2APOLBL3MBTL1SMN1; SMN2PPARA | |
| SCHEMBL29052238 | 0.79 | PPARA (0.53) | KMT2APOLBL3MBTL1RECQLTDP1 | |
| SCHEMBL30253971 | 0.78 | CA12 (0.42) | GRK2KMT2ACTDSP1NPC1RAB9A | |
| SCHEMBL19463254 | 0.77 | MAPT (0.45) | NPC1PPARAALDH1A1MAPTTP53 | |
| SCHEMBL30253556 | 0.75 | TSHR (0.49) | NPC1RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30672491 | 0.70 | NPC1 (0.51) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29052162 | 0.68 | MAPT (0.41) | KMT2ANPC1RAB9APOLBTDP1 | |
| SCHEMBL29780988 | 0.68 | MAPT (0.41) | KMT2ANPC1RAB9APOLBTDP1 | |
| SCHEMBL19429635 | 0.67 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040686-A1 | PYRIDAZINONE COMPOUND, PREPARATION METHOD, HERBICIDE COMPOSITION AND USE THEREOF | 江苏中旗科技股份有限公司 | 2023-03-23 | — | — | WO | disclosed |