SCHEMBL8527615

SCHEMBL8527615

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nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 4/20 0.43
▸ ECE1 P42892 1/20 0.36
▸ CD274 Q9NZQ7 3/20 0.36
▸ PDCD1LG2 Q9BQ51 2/20 0.36
▸ OPRM1 P35372 2/20 0.35
▸ OPRD1 P41143 2/20 0.35
▸ CA2 P00918 3/20 0.34
▸ CA1 P00915 2/20 0.34
▸ PRSS1 P07477 1/20 0.33
▸ TMPRSS15 P98073 1/20 0.33
▸ VSIR Q9H7M9 2/20 0.33
▸ CTSC P53634 1/20 0.33
▸ PDCD1 Q15116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29961849 1.00 MME (0.43) MMEECE1CD274PDCD1LG2OPRM1
SCHEMBL8527609 1.00 MME (0.43) MMEECE1CD274PDCD1LG2OPRM1
Water SCHEMBL29655402 0.99 MME (0.43) MMEECE1CD274PDCD1LG2OPRM1
SCHEMBL31453800 0.94 OPRM1 (0.40) MMEECE1CD274PDCD1LG2OPRM1
SCHEMBL30974040 0.92 OPRM1 (0.42) MMEECE1CD274PDCD1LG2OPRM1
SCHEMBL30254475 0.92 OPRM1 (0.39) MMEECE1CD274PDCD1LG2OPRM1
SCHEMBL30997434 0.91 MME (0.38) MMECD274PDCD1LG2OPRM1OPRD1
SCHEMBL8437182 0.91 MME (0.37) MMEECE1CA2CA1
SCHEMBL8437180 0.91 MME (0.37) MMEECE1CA2CA1
SCHEMBL29794242 0.91 MME (0.36) MMEECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 — — US claimed
US-20230084521-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2023-03-16 — — US claimed
CN-115047120-A Dansyl chloride derivatization method for analyzing and detecting dipeptide substances in white spirit Daqu 贵州茅台酒股份有限公司 2022-09-13 — — CN claimed
US-20220105050-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2022-04-07 — — US claimed
WO-2026089754-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 — — WO disclosed
WO-2026089752-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 — — WO disclosed
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 — — US disclosed
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 — — US disclosed
US-20260085097-A1 DARPIN-CONTAINING COMPOSITIONS AND METHODS THEREOF TEXAS A & M UNIV SYS (US) 2026-03-26 — — US disclosed
US-20250312361-A1 FOSPROPOFOL METHODS AND COMPOSITIONS EPALEX CORP (US) 2025-10-09 — — US disclosed
EP-4626911-A1 RECOMBINANT POLYPEPTIDE Humble Bee Limited (NZ) 2025-10-08 — — EP disclosed
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 — — US disclosed
CN-108610418-B Anti-complement C1s antibodies and uses thereof 美国比奥维拉迪维股份有限公司 2022-11-01 — — CN disclosed
CN-115243713-A Methods and compositions for delivering modified lymphocyte aggregates 埃克苏马生物技术公司 2022-10-25 — — CN disclosed
CN-115212289-A Probiotic active peptide composition and application thereof 上海朗泰凯尔生物技术有限公司 2022-10-21 — — CN disclosed
CN-115047120-A Dansyl chloride derivatization method for analyzing and detecting dipeptide substances in white spirit Daqu 贵州茅台酒股份有限公司 2022-09-13 — — CN disclosed
US-20220265686-A1 FOSPROPOFOL METHODS AND COMPOSITIONS EPALEX CORPORATION 2022-08-25 — — US disclosed
WO-2022169520-A1 FOSPROPOFOL METHODS AND COMPOSITIONS EPALEX CORPORATION (US) 2022-08-11 — — WO disclosed
US-20220105050-A1 PROPOFOL PRODRUG METHODS AND COMPOSITIONS EPALEX CORPORATION 2022-04-07 — — US disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312361-A1 FOSPROPOFOL METHODS AND COMPOSITIONS FOS, FOSB, PFAS MME 2240/4885ECE1 4230/4885CD274 3811/4885
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES MUC1, VIP, LGALS4 MME 522/4885ECE1 2597/4885CD274 4224/4885
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FGF23, FIBP, PTMS MME 1131/4885ECE1 3158/4885CD274 3811/4885
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS MME 2240/4885ECE1 4230/4885CD274 3811/4885
US-20260085097-A1 DARPIN-CONTAINING COMPOSITIONS AND METHODS THEREOF FMNL1, ACTL6A, ANKK1 MME 493/4885ECE1 2563/4885CD274 3159/4885
US-20220265686-A1 FOSPROPOFOL METHODS AND COMPOSITIONS FOS, FOSB, PFAS MME 2240/4885ECE1 4230/4885CD274 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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