Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885473 | 1.00 | PDK2 (0.44) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL23885494 | 0.82 | L3MBTL1 (0.47) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL23885408 | 0.81 | CYP1A2 (0.50) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL30254662 | 0.81 | CYP1A2 (0.50) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL23885579 | 0.79 | PDK1 (0.53) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL23885415 | 0.78 | PDK1 (0.49) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL30997533 | 0.78 | PDK1 (0.38) | PDK2PDK1PDK3PDK4KMT2A | |
| SCHEMBL306012 | 0.78 | MEN1 (0.46) | PDK2PDK1PDK3PDK4L3MBTL1 | |
| SCHEMBL17824803 | 0.78 | KDM4E (0.53) | PDK2PDK4KMT2AF2MAPT | |
| SCHEMBL28429236 | 0.78 | F2R (0.51) | KMT2AF2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |