Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732717 | 0.83 | ALDH1A1 (0.49) | F2RKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17824803 | 0.79 | KDM4E (0.53) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL30254597 | 0.78 | PDK2 (0.44) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL23885473 | 0.78 | PDK2 (0.44) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL29480975 | 0.75 | F2R (0.43) | F2RKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL28655848 | 0.74 | HSD17B10 (0.63) | KMT2AMEN1ALDH1A1KDM4EHTT | |
| SCHEMBL5928724 | 0.74 | TSHR (0.68) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL9573815 | 0.74 | HSD17B10 (0.44) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL30997533 | 0.73 | PDK1 (0.38) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29279663 | 0.73 | TSHR (0.52) | KMT2AMEN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479814-A | Fused pyridines as H-PGDS inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-07-31 | — | — | CN | disclosed |