Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.38 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670084 | 1.00 | CYP3A4 (0.43) | CYP3A4CYP3A5ALDH1A1CDC7DBF4 | |
| SCHEMBL3152938 | 0.81 | ALDH1A1 (0.47) | CYP3A4CYP3A5ALDH1A1BRD4LRRK2 | |
| SCHEMBL30495981 | 0.74 | AKT2 (0.44) | CDC7DBF4NEK2LRRK2PI4KA | |
| SCHEMBL29031959 | 0.74 | AKT2 (0.44) | CDC7DBF4NEK2LRRK2PI4KA | |
| SCHEMBL21263216 | 0.70 | AURKA (0.38) | ROCK2ROCK1CDC42BPACDC42BPBLRRK2 | |
| SCHEMBL3974202 | 0.69 | ALDH1A1 (0.46) | CYP3A4CYP3A5ALDH1A1BRD4LRRK2 | |
| SCHEMBL323982 | 0.69 | ALDH1A1 (0.52) | CYP3A4CYP3A5ALDH1A1BRD4LRRK2 | |
| SCHEMBL22830483 | 0.69 | ALDH1A1 (0.46) | CYP3A4CYP3A5ALDH1A1BRD4LRRK2 | |
| SCHEMBL1165562 | 0.69 | ALDH1A1 (0.46) | CYP3A4CYP3A5ALDH1A1CDC7DBF4 | |
| SCHEMBL2493987 | 0.69 | BRD4 (0.51) | ALDH1A1BRD4LRRK2PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752498-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2023-06-28 | — | — | EP | claimed |
| EP-3752498-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-11608335-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2023-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11608335-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | CYP3A4 4648/4885CYP3A5 4065/4885ALDH1A1 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.