Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255027 | 0.81 | CYP3A4 (0.43) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL3670084 | 0.81 | CYP3A4 (0.43) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL323982 | 0.74 | ALDH1A1 (0.52) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL2001255 | 0.73 | ALDH1A1 (0.42) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL19778900 | 0.69 | ALDH1A1 (0.46) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL3974202 | 0.69 | ALDH1A1 (0.46) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL22830483 | 0.69 | ALDH1A1 (0.46) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL1165562 | 0.69 | ALDH1A1 (0.46) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL7108989 | 0.69 | PI4KA (0.50) | ALDH1A1BRD4CYP3A4CYP3A5PI4KA | |
| SCHEMBL2493987 | 0.69 | BRD4 (0.51) | ALDH1A1BRD4PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233493-A1 | Macrolides | Pfizer Products Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-1836211-B1 | MACROLIDES | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |