SCHEMBL302564

SCHEMBL302564

CCCCCCCCCCCCOc1ccc(C(=O)Oc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.82
TSHR P16473 1/20 0.82
PLA2G4B P0C869 7/20 0.80
RARB P10826 3/20 0.76
NPC1 O15118 3/20 0.72
LMNA P02545 3/20 0.72
NFKB1 P19838 3/20 0.72
NFKB2 Q00653 3/20 0.72
RELA Q04206 3/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
PLA2G4A P47712 1/20 0.72
CYP1A2 P05177 1/20 0.70
CYP3A4 P08684 1/20 0.70
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
CYP2C19 P33261 1/20 0.70
HTT P42858 1/20 0.62
POLB P06746 1/20 0.62
MAPT P10636 1/20 0.62
PRSS1 P07477 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9665666 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL14262242 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL5233946 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL304398 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL9128354 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL5364776 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
SCHEMBL1160588 1.00 TP53 (0.82) TP53TSHRPLA2G4BRARBNPC1
Hydrochloric Acid SCHEMBL9126854 0.99 TP53 (0.80) TP53TSHRPLA2G4BRARBNPC1
Hydrochloric Acid SCHEMBL11873498 0.99 TP53 (0.80) TP53TSHRPLA2G4BRARBNPC1
Hydrochloric Acid SCHEMBL8861837 0.99 TP53 (0.80) TP53TSHRPLA2G4BRARBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092712-B2 Bent-core LC decorated gold nanoclusters Ridout & Maybee LLP (CA) 2012-01-10 US disclosed
US-20110062385-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS UNIVERSITY OF MANITOBA (CA) 2011-03-17 US disclosed
WO-2009052632-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS UNIVERSITY OF MANITOBA (CA) 2009-04-30 WO disclosed
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
US-4952337-A FERROELECTRIC MATERIALS THE SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM, OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1990-08-28 US disclosed
EP-0210215-B1 FLUORINATED PHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1990-03-14 EP disclosed
US-4769176-A Biphenyl esters and liquid crystal materials and devices containing them THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1988-09-06 US disclosed
EP-0210215-A1 Fluorinated phenyl esters and liquid crystal materials and devices containing them. SECR DEFENCE BRIT (GB) 1987-02-04 EP disclosed
WO-1986004327-A1 BIPHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1986-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110062385-A1 BENT-CORE LC DECORATED GOLD NANOCLUSTERS SLC6A13, SLC6A6, LGALS3 TP53 3948/4885TSHR 1096/4885PLA2G4B 3812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.