SCHEMBL30257589

SCHEMBL30257589

Clc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccc(-c3ccccc3)cc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.46
CYP1A2 P05177 1/20 0.42
MAP4K4 O95819 1/20 0.40
TSPO P30536 2/20 0.39
AKR1B1 P15121 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
PTGES2 Q9H7Z7 4/20 0.36
PTGES O14684 1/20 0.36
APAF1 O14727 1/20 0.35
KDM4E B2RXH2 3/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 2/20 0.35
MAPK14 Q16539 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27012163 0.96 CYP1A2 (0.46) DNM1CYP1A2MAP4K4APAF1KDM4E
SCHEMBL21708988 0.93 TSPO (0.43) DNM1TSPOAPAF1KDM4EATM
SCHEMBL17714934 0.92 DNM1 (0.46) DNM1CYP1A2MAP4K4TSPOAKR1B1
SCHEMBL30256945 0.92 DNM1 (0.46) DNM1CYP1A2MAP4K4TSPOAKR1B1
SCHEMBL27012175 0.91 L3MBTL1 (0.44) DNM1CYP1A2MAP4K4TSPOPTGES2
SCHEMBL30257199 0.89 DNM1 (0.38) DNM1CYP1A2MAP4K4APAF1KDM4E
SCHEMBL29892513 0.89 DNM1 (0.38) DNM1CYP1A2MAP4K4APAF1KDM4E
SCHEMBL29104448 0.89 DNM1 (0.38) DNM1CYP1A2MAP4K4APAF1KDM4E
SCHEMBL24923755 0.89 ATM (0.41) DNM1TSPOAPAF1KDM4EATM
SCHEMBL25671853 0.89 ATM (0.41) DNM1TSPOAPAF1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013615-A1 AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2023-02-09 WO disclosed