Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321845 | 1.00 | GAA (0.62) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL6986276 | 0.98 | GAA (0.61) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL132755 | 0.85 | GAA (0.68) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL1403643 | 0.84 | GAA (0.72) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL27529005 | 0.83 | GAA (0.66) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL27966618 | 0.83 | CASP1 (0.44) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL27720317 | 0.83 | CASP1 (0.44) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL9705197 | 0.82 | GAA (0.65) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL6168887 | 0.82 | GAA (0.66) | GAAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL7623605 | 0.82 | GAA (0.70) | GAAALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |